TNF and herpes simplex infectious disease: The enrichment analysis of 820 DE mRNAs pointed out 26 significantly enriched KEGG pathways (EASE score27 <0.05, p.BH <0.05) with ‘TNF signalling pathway’, ‘Influenza A’, ‘NF-κB signalling pathway’, ‘Herpes simplex infection’, ‘Cytosolic DNA-sensing pathway’, ‘Toll-like receptor signalling pathway’, ‘Jak-STAT signalling pathway’, ‘NOD-like receptor signalling pathway’, ‘Cytokine-cytokine receptor interaction’ and ‘Measles’ being the ten most enriched pathways (Fig. 5).