GJB2 variants are the most common cause of NSHL, and its detection rate differs depending on the ethnicity and country of origin; 20% in Caucasians of European descent8, 43% in Israelis9, 21~27% in Japan and Chinese10–12, 17% in Tunisians13, 17% in Iranian14, 14% in Australians15, and 10% in Koreans3,16. Here, GJB2 is linked to nodular sclerosis classical Hodgkin lymphoma.