DICER1 and Hepatitis: Mice lacking miR-122 or Dicer in liver share with Cnot3LKO mice several phenotypic abnormalities, such as lipid accumulation, increase of binucleate hepatocytes and hepatitis, and they also share specific changes in gene expression (Sekine et al., 2009; Hsu et al., 2012; Tsai et al., 2012; Hsu et al., 2016).