TP53 and lung cancer: As a first step to investigate the relationship between p53 mutant status and the clinicopathologic features of lung cancer patients, the statistic analysis of clinicopathologic characteristics in 78 NSCLC patients was showed the mut-p53 was both positively related to the nodes metastasis (P = 0.0267) and TNM stage (P = 0.0399) (Table 1).