TNF and rheumatoid arthritis: Tumor necrosis factor-α (TNF-α) antagonists, most of which are monoclonal antibodies (infliximab, golimumab, adalimumab), became a widespread treatment for autoimmune diseases such as rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel diseases, psoriasis, psoriatic arthritis, hidradenitis suppurativa and uveitis.