Recent studies have uncovered several urinary and plasma biomarkers that can predict kidney injury in patients with cirrhosis.[14,25,26] In particular, increased levels of interleukin-18, kidney injury molecule-1, liver-type fatty acid binding protein, and neutrophil gelatinase-associated lipocalin are specific indicators of structural injury rather than surrogate markers for deceased filtration. Here, LCN2 is linked to Cirrhosis.