CSF1R and Hereditary diffuse leukoencephalopathy with axonal spheroids and pigmented glia: On the other hand, a mutant Csf1r mouse strain with a haploinsufficient allele resembled HDLS‐like symptoms (Chitu et al., 2015), but some neuropathological findings differed from patients with HDLS (Konno, Kasanuki et al., 2018).