The staining density of FOXP3, a crucial marker for Tregs, and CD33, one of tumor promoting MDSC immune markers, was not significantly correlated to HDL‐C level in the human specimens of the current study, although HDL‐C was demonstrated to inhibit the accumulation of MDSC in murine tumor models.18, 19 However, considering the diversity of CD33 staining immune cells, other immune markers and multiparametric flow cytometry was needed to further confirm the results. Here, FOXP3 is linked to neoplasm.