NF‐κB signalling is the most important pathway to regulate inflammatory response in metabolic diseases.5, 6 As Figure 3B,C showed, miR‐802 sponge could inhibit the phosphorylation and degradation of IκB in obese mice, as compared with Ctrl sponge‐treated obese mice (P < 0.01). Here, NFKB1 is linked to metabolic disease.