HNF1B and obesity due to melanocortin 4 receptor deficiency: Intestinal miR‐802 affected the biological efficacy of angiotensin II in gastrointestinal system.31 In obesity, up‐regulated hepatic miR‐802 impaired glucose metabolism through silencing of Hnf1b. 16 In type 2 diabetic patients, the circulating miR‐802 was also significantly increased and closely correlated with metabolic parameters.32 These studies also addressed miR‐802 and inflammatory response had a positive feedback in the development of tissue dysfunction.