More importantly, renal miR‐802 could mediate potassium channel activity through suppressing caveolin‐1 expression.36 In present study, we found up‐regulation of miR‐802 closely associated with obesity‐induced renal dysfunction, including structural disorders, fibrosis and accumulated inflammatory response. This evidence concerns the gene KCNA3 and obesity due to melanocortin 4 receptor deficiency.