Nevertheless, the overall survival in the whole study population with mutant NPM1 or CEBPA were lower than those in patients with completion of 4 cycles of consolidation chemotherapy, and in the previous studies [6, 14–16, 29], which the causes of shorter OS in the entire population was numerous patients died from febrile neutropenia with bacterial sepsis and few patients also refused chemotherapy. This evidence concerns the gene CEBPA and bacterial infectious disease with sepsis.