The proportion of sAD was significantly larger (P < 0.01) among the patients with IgG-reactivity to any of the four antigens compared to the group of patients without any reactivity, whereas the proportion of patients with rhinoconjunctivitis and/or asthma, elevated total plasma IgE and positive Phadiatop was similar (Fig. 6b compared to Fig. 6g). The gene discussed is IGHE; the disease is asthma.