TNFRSF21 and breast cancer: In addition, we analyzed coefficient of determination (R2) between SAA1/2 and TNBC-dominant IL and TNF subfamilies in 51 human BC cell lines as follows: R2 = 0.86 with IL1A, R2 = 0.88 with IL1B, R2 = 0.59 with CXCL8, R2 = 0.62 with IL32, R2 = 0.08 with IL27RA, R2 = 0.017 with CD70, R2 = 0.11 with TNFSF9, R2 = 0.027 with TNFRSF21, R2 = 0.002 with TLR1, and R2 = 0.002 with TLR2 (Supplementary Figure 4).