NFE2L2 and acute respiratory distress syndrome: Furthermore, the transfection of Nrf2 is also able to reinforce the efficacy of human amniotic mesenchymal stem cells (hAMSCs) to inhibit inflammation, fibrosis, and lung injury and promote hAMSCs to differentiate into type II alveolar epithelial (AT II) cells with enhanced activity of Nrf2 in an LPS-induced mouse ARDS model [108].