Microarray data found that the expression of four lncRNAs significantly changed in HD brains: NEAT1 (nuclear paraspeckle assembly transcript 1) and TUG1 are upregulated, and DGCR5 (DiGeorge syndrome critical region gene 5) and MEG3 (maternally expressed 3) are downregulated. This evidence concerns the gene MEG3 and Huntington disease.