The ROC curve revealed that the area under the curve (AUC) of BNP for predicting the positive outcome of HF was 0.999 (95% CI: 0.998-1.000, P < 0.0001; Figure 3(a)), while the AUC of IL-11 for predicting the positive outcome of HF was 0.825 (95% CI: 0.771-0.878, P < 0.0001; Figure 3(a)); the diagnostic value of BNP in HF was better than IL-11 (P < 0.0001; Figure 3(a)). This evidence concerns the gene NPPB and hydrops fetalis.