NPM1 and acute myeloid leukemia: Of 277 patients, 9 (3%) were excluded due to violation of inclusion/exclusion criteria: no diagnosis of AML, n = 3; AML with NPM1 mutation, n = 1; presence of Philadelphia chromosome, n = 1; organ insufficiency (renal failure), n = 1; withdrawal of informed consent, n = 2; other reason (extramedullary manifestation of AML in spleen), n = 1.