In CTRF+ individuals, mRNA levels of TSPAN8 associated with T2D family history (p < 0.01), of IGF2BP2 tv7 with serum glucose levels, while in the total group of controls, KCNQ1 tv1 levels reversely with BMI, central obesity, glucose and LDL (mg/dl) levels (p < 0.05). The gene discussed is IGF2BP2; the disease is type 2 diabetes mellitus.