The levels of CDKN2A tv3 were as well significantly associated with serum insulin levels in T2D patients (p < 0.01), while these of CDKN2A tv4 correlated positively with BMI and waist-to-hip ratio and negatively with serum HDL levels (mg/dl) in the CTRF+ subgroup (p < 0.05). The gene discussed is INS; the disease is type 2 diabetes mellitus.