Results showed that tumor growth rate was significantly faster in the H19 overexpression group than in the control group; bortezomib treatment still showed that the overexpression group was faster than the control group; and in the third group we saw that miRNA-29b did inhibit tumor growth, but when pcDNA-H19 was added, the growth rate of the tumors increased again. The gene discussed is H19; the disease is neoplasm.