As presented in Table 3, every incremental unit of either PDCD1 and CD274 was associated with improved OS (PDCD1, HR 0.02, 95% CI 0.00–0.36, P = 0.007; CD274, HR 0.12, 95% CI 0.02–0.81, P = 0.030) and DFS (PDCD1, HR 0.08, 95% CI 0.01–0.83, P = 0.034; CD274, HR 0.19, 95% CI 0.04–0.97, P = 0.045) even following adjustment for tumor size, grade, age and lymph node status. This evidence concerns the gene CD274 and neoplasm.