HDAC6 and melanoma: Since the presence of memory T-cells is associated with patient response to TIL adoptive cell therapy [33], we evaluated the ability of HDAC6-selective inhibitors to impact on the phenotype of TILs isolated from surgically resected melanoma tumors, by expanding TILs ex vivo in 6000IU/mL IL-2 [12], plus ACY-1215 or DMSO.