Secondly, miR-767-5p mimics significantly increased cell viability and proliferation of MM cells, promoted cell cycle progression with down-regulation of CDK6, CDK4, Cyclin D1 and Cyclin E, while up-regulation of p21Cip1, suggesting the promotion ability of cell progression for miR-767-5p. The gene discussed is CDK4; the disease is Miyoshi myopathy.