Similarly, the overexpression of 3 ‘UTR wild-type FOXP2 group reversed the overexpression of miR-376b-3p in inhibiting proliferation, migration, and invasion of glioma cells, and reduced the apoptosis rate of glioma cells induced by overexpression of miR-376b-3p (P < 0.01) (Additional file 2: Figure S2D-F). The gene discussed is FOXP2; the disease is central nervous system cancer.