In this study, the expression of FOXP2 in glioma tissues was higher than that in normal brain tissues; and the expression of high grade pathological tissue was higher than that of low grade; the expression in glioma U87 and U251 cells was significantly higher than that in HA cells, the above differences were statistically significant (P < 0.01) (Fig. 3a, b). This evidence concerns the gene FOXP2 and central nervous system cancer.