RBP4 and amyotrophic lateral sclerosis: Both cell types were enriched for another FMRP binding motif (GGACAAG: VGAT, p = 1.5E-05; RBP4, p = 1E-15) as well as a binding site for FUS RNA binding protein (GGUG: VGAT, p = 5.3E-06; RBP4, p = 5E-26; Fig. 5A), a gene clearly implicated in amyotrophic lateral sclerosis (ALS; Deng et al., 2014).