In univariate Cox proportional hazards regression analysis, the factors significantly associated with OS of CCRCC patients were age (P = 0.006), tumor size (P < 0.001), tumor stage (P < 0.001), tumor necrosis (P = 0.006), Nu-FAM83H (P < 0.001), Cy-FAM83H (P < 0.001), Nu-PANX2 (P < 0.001), and Cy-PANX2 (P < 0.001) (Table 3). The gene discussed is SACK1H; the disease is neoplasm.