Kaplan-Meier analysis revealed that ccRCC patients in CXCL13+CXCR5+ group have a worst overall survival and ccRCC patients in CXCL13−CXCR5− group have a best overall survival (Log rank P < 0.05) (Figure 4C). Here, CXCL13 is linked to nonpapillary renal cell carcinoma.