lncRNA SRA inhibits the transcription of forkhead box protein O1 (FoxO1) through an insulin-independent pathway in hepatocytes, thereby reducing the expression of the downstream gene adipose triglyceride lipase (ATGL) and subsequently lowering the FFA β-oxidation of hepatocytes, resulting in hepatic steatosis [100]. Here, PNPLA2 is linked to Hepatic steatosis.