As indicated in Table 5 and Figures 7(a)–7(e), we observed that mRNA expression of TGF-β1, TβRI, and TβRII in BLM, BLM+ Pred, and BLM+YYYQ-L group were significantly higher than that of control group on both day 14 and day 28 (p <0.01 or p <0.05). This evidence concerns the gene TGFB1 and Bloom syndrome.