It is also found that other ingredients of YYYQ, such as radix lithospermi, can inhibit the expression of endothelial growth factors to reduce angiogenesis, thereby preventing the progression of pulmonary fibrosis [28], whereas ligustrazine can decrease TGF-β1 and CTGF levels in pulmonary fibrotic rats [29]. Here, TGFB1 is linked to pulmonary fibrosis.