In order to determine the molecules involved in IL13Rα2-mediated angiogenesis in melanoma, we performed Angiogenesis Antibody Array using the lysates of tumour tissues derived from xenografted SK-MEL-28 and SK-IL13Rα2 cells (unpublished data) and identified multiple angiogenesis-related molecules including amphiregulin. The gene discussed is AREG; the disease is neoplasm.