TP53 and systemic lupus erythematosus: Using a Benjamini-corrected p-value threshold of 0.05, six significantly enriched pathways were identified with the p53 signaling pathway being the most affected (fold enrichment 5.0, p = 1.2E-6; Fig. 3C), followed by the Fanconi anemia pathway (p = 10E-6), Cell cycle (p = 5.4E-7), Pyrimidine metabolism (p = 7.3E-4), Systemic lupus erythematosus (p = 9.5E-4) and the Forkhead box O (FoxO) signaling pathway (p = 9.5E-4).