PKD2 and lung adenocarcinoma: Kaplan-Meier survival curves demonstrated high level of PKD2 expression to be a significantly unfavorable prognostic factor for overall survival (OS) (p = 0.015) and progression free survival (PFS) (p = 0.006), while high expression of E-cadherin predicted good outcomes in patients with lung adenocarcinoma (OS: p = 0.003; PFS: p = 0.003) (Fig. 2C–F).