Significant differences were observed in the histopathologic differentiation (poor vs well & moderate, P = 0.026), TNM stage (P < 0.001), tumor size (P = 0.030), lymphatic invasion (P < 0.001), perineural invasion (P < 0.001), and CEA level (P < 0.001) between the patient group with and the group without recurrence. Here, CEACAM5 is linked to neoplasm.