BRAF and melanoma: This was true when viral peptide was injected into palpable, poorly immunogenic melanoma tumors of Braf/Pten mice, or into MC38 colon adenocarcinoma or B16 melanoma i.d. injected tumor cell lines, with total clearance of the moderately immunogenic MC38 observed in some mice (Fig. 1d–f and Supplementary Figure 3).