We also tested growth of B16 tumors in mice that did not receive OT-I T cells but rather had endogenous B8R and N-specific memory CD8+ T cells due to prior exposure to vesicular stomatitis virus (VSV) and recombinant vaccinia virus expressing the N epitope derived from VSV; tumor control was similar in response to N and B8R peptides, indicating that this phenomenon did not depend on the experimental use of transgenic T cells (Fig. 1g). The gene discussed is CD8A; the disease is neoplasm.