MITF and focal segmental glomerulosclerosis: In podocytes, INF2 plays a key role as a regulator of function and structure of the actin cytoskeleton (Safarikova et al., 2018) and mutations in INF2 are known to cause genetic forms of FSGS, which underlines the potential relevance of the mitf-INF2 axis for patients suffering from FSGS (Safarikova et al., 2018; Caridi et al., 2014).