ACE and hydrops fetalis: Pharmacological interventions for CVDs and HF include prescription of statins, neuro-hormonal blockage by, e.g., angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers and β-blockers, and instrumentation via, e.g., an implantable cardiac defibrillator (ICD) in order to prevent sudden death caused by arrhythmic events.