CD8A and neoplasm: An inverse correlation between post-NACT tumor stage and the grade of the Immunoscore-like dual marker combinations of CD3/CD8 and CD3/CD20 (p = 0.0254 and p = 0.0144) were observed, indicating that higher level infiltration of CD3+ T cells either with CD8+ T cells or with CD20+ B cells in both tumor regions was associated with a reduced tumor size after therapy.