SERPINB3 and hepatocellular carcinoma: An inverse correlation between miR-122 and SerpinB3 was also found in two HCC patient cohorts, both at mRNA and protein levels, as determined by qPCR and IHC analysis on tissue microarray slides (Figure 3), confirming further the results obtained in preclinical models and strongly suggesting a post-transcriptional regulation of SerpinB3 by miR-122 in HCC.