In tissues, Cx30.2 was very rarely detected in common nevi (2/58, 3%) (Figure 3K) or dysplastic nevi (2/45, 4%) but it was more frequent in primary melanomas (14/60, 23%; 2/18, 11% of thin and 8/25, 32% of thick) and in metastatic cases (4/17, 24%) (Figure 3L,M) as a cytoplasmic and frequently paranuclear reaction. This evidence concerns the gene GJD3 and dysplastic nevus.