GJA1 and melanoma: In GSE7553 arrays, metastatic melanomas showed downregulated GJA1 (Cx43; LogFC = −1.9; p < 0.001), GJB2 (Cx26; LogFC = −4.6; p < 0.001), GJB3 (Cx31; LogFC = −3.2; p < 0.001), GJB5 (Cx31.1; LogFC = −2.5; p < 0.001) and GJB6 (Cx30; LogFC = −7.1; p < 0.001) gene expression compared to primary (including in situ) melanomas [27].