Some well-studied examples include the following: (1) the β-site amyloid β-protein precursor (APP) cleaving enzyme 1 antisense RNA (BACE1-AS) in Alzheimer’s disease (AD); (2) phosphatase and tensin homolog (PTEN)-induced kinase 1 antisense (PINK1-AS) which is stabilizing its protein-coding pendant PINK1 in Parkinson’s disease (PD) [100,101,102]; and (3) brain-derived neurotrophic factor antisense (BDNF-AS) in Huntington’s disease (HD) [103,104]. The gene discussed is PTEN; the disease is early-onset autosomal dominant Alzheimer disease.