POLG and idiopathic pulmonary fibrosis: In the IPF patients, the MFN2 expression level in the homozygous AluYb8MUTYH group (P/P) was significantly higher than that in the heterozygous group (A/P), and the POLG and ATG7 mRNA levels in the P/P patients were lower than those in the A/P patients (Figure 2G).