BAP1 and clear cell renal carcinoma: BAP1 tumor predisposition syndrome (BAP1 -TPDS) OMIM #614327 is associated with an increased risk for uveal melanoma (UM), malignant mesothelioma (MMe), cutaneous melanoma (CM), clear cell renal cell carcinoma (RCC) and potentially other cancers such as breast cancer [1–3].