ERBB2 and hepatocellular carcinoma: In the past three decades, the most studies on HER2 expression in HCC were prone to claim that HER2 is rarely overexpressed in HCC and may not play an essential role in the process of HCC.11, 12, 13, 14, 15 Alternatively, other studies have demonstrated that HER2 expression was found elevated in 30%‐40% of HCCs and may be an independent prognostic factor.16, 17, 18, 19 HER2 expression and its function in HCC development needs further explorations.