Previous reports have noted that CXCR2 affects immune tolerance at the maternal fetal interface and decidual spiral artery remodeling, and therefore may contribute to preeclampsia and miscarriage (Kang et al., 2016; Pitman, Innes, Robson, Bulmer, & Lash, 2013). The gene discussed is CXCR2; the disease is preeclampsia.