Colorectal cancer tumors that have increased neoantigen production due to MMR deficiency also have higher levels of tumor infiltrating lymphocytes (TILs) and increased programmed death ligand‐1 (PDL‐1) protein expression (Germano et al., 2018; Kim et al., 2016; Llosa et al., 2015). This evidence concerns the gene CD274 and neoplasm.