Multivariate Cox regression survival analysis adjusting for age, T stage, LNM, pathological grade and GOT protein level consistently reported strong correlation between GOT2 overexpression and shorter survival (P = 0.027, Hazard ratio (HR) = 2.383, 95% CI 1.104–5.141) (Fig. 6F, Additional file 1: Table S7), indicating that GOT2 expression was an independent prognostic factor for outcome in BC. Here, GOT2 is linked to breast cancer.