In all patients with GIST, patients with high PD‐L1 expression showed a higher rate of relapse than those with low PD‐L1 expression, and the PD‐L1 expression in the 21 recurrent patients from the follow‐up study was similar to that of the 15 patients who relapsed before surgery and higher than that of the high‐risk GIST patients with low PD‐L1 expression, which showed that PD‐L1 expression affected clinical outcome in high‐risk GIST patients (Figure 1E). The gene discussed is CD274; the disease is gastrointestinal stromal tumor.