LCN2 and acute kidney injury: Likewise, a recent abstract presented a controlled hemorrhagic shock model in anesthetized dogs treated with a bolus of either 6% tetrastarch, 4% succinylated gelatine, fresh whole blood, or an isotonic crystalloid, HES did not lead to a greater incidence of AKI (assessed by different renal biomarkers, e.g., urinary NGAL, and renal histopathology) compared to the other resuscitations fluids (107).