An increase inthe concentration of CCL5 in the cerebrospinal fluid can serve as one of themarkers of MS progression [35].Proinflammatory cytokine TNFSF14, the fourteenth member of the superfamily oftumor necrosis factors, can function as a co-stimulator in lymphocyte cellactivation, can stimulate T cell proliferation, and induce apoptosis of sometypes of tumor cells. The gene discussed is TNFSF14; the disease is neoplasm.