AGT and renal fibrosis: There is a large number of clinical data confirming that angiotensin converting enzyme (ACEI) inhibitors and angiotensin receptor blockers (ARB) not only can reduce the system pressure and slow down the progression of renal disease, but also can reduce the capillary pressure and the filtration protein, delay cell proliferation, and alleviate renal fibrosis which is mediated by angiotensin II [15, 16].