DROSHA and colonic neoplasm: Although little evidence exists that rs17410035 has an impact on DROSHA gene expression or miRNA biogenesis (which could affect gene expression) it has been associated with increased colon cancer (OR = 1.22, p-value = 0.014) (Mullany et al., 2016) and cancer of the head and neck (OR = 2.28, p-value = 0.016) (Zhang et al., 2010).