We have selected 10 mRNAs which were differentially expressed in both HD iPSC lines (OTOGL, TRIM69, CNTNAP3B, MEIOB, C3, PARP12, XDH, CDKN1A, ZFP30, WDR72), 4 mRNAs which were differentially expressed in HD71Q iPSC lines (PIWIL2, HIST1H3C, FAM65B, PDGFB) and 3 mRNAs differentially expressed in HD109Q iPSC line (TP53, PHLDA3, TRIM22). The gene discussed is C3; the disease is Huntington disease.